Radical perfluoroalkylation – easy access to 2-perfluoroalkylindol-3-imines via electron catalysis
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چکیده
منابع مشابه
Radical perfluoroalkylation - easy access to 2-perfluoroalkylindol-3-imines via electron catalysis.
Arylisonitriles (2 equivalents) react with alkyl and perfluoroalkyl radicals to form 2-alkylated indole-3-imines via two sequential additions to the isonitrile moiety followed by homolytic aromatic substitution. The three component reaction comprises three C-C bond formations. The endocyclic imine functionality in the products is more reactive in follow up chemistry and hydrolysis of the exocyc...
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2016
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c6cc02284g